Abstract

Hair loss has a significant influence on psychological distress and is associated with low self-esteem and depression. Treatment options for androgenic alopecia are very limited and include topical minoxidil and oral finasteride (FDA approved) either alone or in combination. However, there are several reported side effects such as headache and increase in other body hairs for minoxidil whereas loss of libido has been reported with oral finasteride. Finasteride also interferes with genital development in a male fetus and is contraindicated in pregnant women and those likely to become pregnant. PRP contains high concentrations of over 20 growth factors that are actively secreted from the α-granules of platelets. (Among those thought to stimulate hair regrowth are platelet-derived growth factor, transforming growth factor, vascular endothelial growth factor (VEGF), epidermal growth factor, fibroblast growth factor, connective tissue growth factor, and insulin-like growth factor IGF-1 ) PRP has already attracted attention in plastic surgery, orthopaedic surgery and cardiac surgery ,we study the role of platelet rich plasma and platelet poor plasma in treatment ofAGA in both males and females