Ectoine is a substance produced by extremophiles and is naturally used by them as a protection against adverse environmental conditions in which they live. Scientific contributions discuss its excellent effect through cosmotropic properties, prevention of secondary messengers release in a cell and transcription factors. The influence over lipid layer of cell membrane and its preventive effect as a UV filter were also demonstrated. What is more, its anti-oxidative effect was established. Ectoine works as immunostimulant and also has anti-inflammatory and anticancer properties. Those attributes are a dominating factor in the use of ectoine's properties after the skin fractionation treatment with CO2 laser. In the following work, the influence of ectoine over skin parameters was described focusing on redness, moisturization and TEWL after prior use of CO2 laser. The obtained result of conducted research proves the positive effect of dermocosmetics with ectoine content in the process of skin healing.